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Secrets of Batch Process Scale-Up
April 10, 2018
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Practical Approaches to Design of Experiments (DoE) for Chemical Process R&D

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Apr 10, 2018 - Apr 11, 2018
9:00 am

Metro Meeting Centers
101 Federal St
Boston MA 02110


Precedent and experience compel many chemists to use OVAT experimentation in spite of its incomplete nature, and in spite of its inability to detect factor interactions, e.g., cases when the impact of one factor depends on the level of another factor. When such interactions occur between scale dependent and scale independent factors, ignoring such factor interactions can lead to high risk process scale-up and technology transfer.

Participants will learn how to design effective screening experiments, how to use response surface methods for reaction and analytical method development, how to design robust processes, and how to quantify the risk associated with the implementation of the processes developed. Several commercial DoE software platforms will be reviewed.

For the benefit of process scientists, engineers, formulators*, analytical chemists and manufacturing personnel, this course includes highly interactive, hands-on workshops.


Scientific Update
Other Sponsor

Name: Dr Claire Francis
Organization: Scientific Update Ltd
Email: info@scientificupdate.com
Contact Address: Scientific Update Ltd, Maycroft Place, Stone Cross, Mayfield, East Sussex, TN20 6EW, UK


Event Tags
Organic Chemistry